LEADS Active Study Page

Welcome LEADS Study staff, coordinators, and PI's.

This section encompasses study specific tools and videos for your reference. If you have any questions, comments, or new ideas please contact NCRAD by email or phone (800) 526-2839 or directly at (317) 278-1170.

CI (Cognitively Impaired) Participants

Baseline

M12

M24

M36

M48

RNA

Serum

Plasma

DNA

PBMC

EDTA for CLIA testing**

CSF

**Please note that this EDTA tube is used for the purpose of confirmation testing and is only drawn during the Baseline visit for CI participants.

CN (Cognitively Normal) Participants

Baseline

M12

M24

RNA

Serum

Plasma

DNA

PBMC

CSF**

** Please note that CSF is to be drawn at Baseline and M24 for CN participants. Can be drawn at M12 if not drawn at Baseline.

Study Resources

Kit Request Module

Please follow the below link to access the Kit Request Module. This link will direct you to a REDCap database where study coordinators and staff may request kits, individual supplies, and/or labels. Study related sites will use the same link for ordering supplies related to blood-based samples and for CSF. Please allow a total of two weeks for kit requests to be compiled and delivered to your site.

Kit Request System

Biological Sample and Shipment Notification Forms

Please use the below downloadable forms to collection information on specimen patient demographics, collection, and processing. We respectfully ask that all completed forms be emailed (alzstudy@iu.edu) or faxed (317-321-2003) prior to shipment. If you complete the form on the website, you can choose to have it emailed automatically to us. We also ask that all shipments include a hard copy of each sample form.

Downloadable Blood Sample Form Web-based Blood Sample Form Downloadable CSF Sample Form Web-based CSF Sample Form

Manual of Procedures

The below downloadable manual for biomarkers was created specifically for the study. Please feel free to explore the manuals through the hyperlinked “Table of Contents”. Questions concerning any part of the manual may be directed to NCRAD at (alzstudy@iu.edu or 800-526-2839) for further clarification.

Manual of Procedures

Related Video Tutorials

Please explore the below videos sponsored by NCRAD for the study.

Plasma Preparation

Serum Preparation

RNA (PAXgeneTM) Processing

Ambient Shipping

Frozen Shipping

Training Slides

Please see the link below for the training slides for the study.

Training Slides