The Pathways Active Study Page

Welcome path Study staff, coordinators, and PI's.

This section encompasses study specific tools and videos for your reference. If you have any questions, comments, or new ideas please contact NCRAD by email or phone (800) 526-2839 or directly at (317) 278-1170.

Collection Tube

Drawn At

Specimen Type

Aliquot Volume

Total Number of Aliquots

Shipping Temperature

1 EDTA (Purple Top) Blood Collection Tube (10 ml)

All Visits


1.5 ml plasma aliquot

Up to 4


0.5 ml plasma aliquot


Kept locally at site

Buffy Coat

1.0 ml buffy coat aliquot



A 25-cell cryobox should contain samples from 3 participant visits. Each participant visit will have up to 4 x Plasma Aliquots and 1 x Buffy Coat Aliquot. This means there should be 12-15 samples per cryobox (9-12 x plasma aliquots and 3 x buffy coat aliquots). An individual participant's samples should be placed in a single row. An empty row should separate each participant's samples from another participant's samples. Plasma samples should be placed to the left, with the buffy coat sample immediately to the right of the last plasma sample. Up to 8 cryoboxes can be put in each shipper.

Kit Request Module

Please follow the below link to access the Kit Request Module. This link will direct you to a REDCap database where study coordinators and staff may request kits, individual supplies, and/or labels. Study related sites will use the same link for ordering supplies related to blood-based samples and for CSF. Please allow a total of two weeks for kit requests to be compiled and delivered to your site.

Kit Request System

Manual of Procedures

The below downloadable manual for biomarkers was created specifically for the Pathways Study. Please feel free to explore the manuals through the hyperlinked “Table of Contents”. Questions concerning any part of the manual may be directed to NCRAD at (, 800-526-2839 or 317-274-7546) for further clarification.

Manual of Procedures

Study Related Video Tutorials

Training Slides

Please see the link below for the training slides for the study.

Training Slides