The goal of the National Cell Repository for Alzheimer’s Disease (NCRAD) is to help researchers find genes that increase the risk for Alzheimer’s disease (AD) and dementia. To accomplish this goal, in 1990, NCRAD was funded by the National Institute on Aging (NIA) to provide researchers with the biological samples and data necessary for finding important genetic factors in AD and dementia.
NCRAD is a national resource where clinical information and biological material (such as DNA, plasma, serum, RNA, CSF, cell lines, and brain tissue) can be stored and requested from individuals with AD and related dementias as well as from individuals without any symptoms of memory loss or dementia. To help identify the genes contributing to the risk for AD, a number of different studies are currently ongoing. These include studies enrolling families with multiple members diagnosed with AD, as well as individuals without a strong family history of AD.
Understanding the causes of AD and dementia will likely lead to better treatments for this devastating disease.