NCRAD Family
The NCRAD Family Study began in 1990 and is still actively recruiting and following subjects. Subjects are contacted annually for updates on diagnoses within their family.
Study Participants
Families with two or more members with early or late onset AD and related dementias. Samples are obtained from affected family members and unaffected relatives (typically over age 60).
Available Data
These families are not evaluated in person and all clinical information is obtained through telephone and medical record review. Therefore, data is limited to the following: family history; demographic data; medical records on the evaluation; diagnosis and treatment of symptomatic subjects; telephone cognitive batter; neuropathological findings when available.
Available Biospecimens
Genomic DNA, Cell Line DNA, Lymphoblastoid Cell Lines (LCLs), PBMCs, Fixed Brain Tissue, Frozen Brain Tissue