Participating in Research
Welcome and thank you for your interest in participating in Alzheimer’s disease research efforts! The National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) often collaborates very closely with research studies and institutions around the world. Through these collaborations, we have compiled a listing of different studies that are currently enrolling subjects and banking samples with NCRAD. We have separated these studies into three categories: “For Those with Dementia”, “For Those with Dementia in Your Family”, and “For Healthy Individuals Who Want to Help”. Please feel free to explore each study by clicking on the study logo. Once clicked, a window will appear offering important information about each study. Information includes location of research sites and how to contact the study coordinator. If you have any additional questions about this webpage, NCRAD Coordinators would be happy to assist. Please call 1-800-526-2839 or email firstname.lastname@example.org to talk with a NCRAD coordinator.
For Those with Dementia
The below studies are specifically enrolling individuals who are currently suffering from various forms of dementia or Alzheimer’s disease (AD). More information about eligibility may be found by clicking on the study logo. Please contact the study coordinator listed on the pop-up information window with questions about enrollment and study participation
4-Repeat Tauopathy Neuroimaging Initiative-Cycle 2
EligibilityIf you are between 40 and 80 years of age with no known history of neurological disease, or with a diagnosis of Progressive Supranuclear Palsy (PSP) or Corticobasal Degeneration (CBD) you may qualify for this.
LocationsCalifornia, Massachusetts, Toronto, Pennsylvania, Minnesota
ContactFor more information, please contact the study coordinators are 415-476-9578 or visit the 4RTNI-2 webpage.
The 90+ Study
EligibilityIf you 90 years of age or older, live in the Southern California area, and willing to undergo clinical assessments, memory testing, and other procedures every 6 months then you may be eligible for this study. Study participants are also asked to agree to undergo one MRI and one amyloid PET scan; as well as, brain donation upon death.
ContactFor more information please visit The 90+ Study website call a study coordinator at 949-768-3635.
Alzheimer’s Disease Research Center
EligibilityPlease contact centers for research and volunteer opportunities. For patients and families affected by Alzheimer's disease, the ADCs offer:
- Help with obtaining diagnosis and medical management (costs may vary—Centers may accept Medicare, Medicaid, and private insurance)
- Information about the disease, services, and resources
- Opportunities for volunteers to participate in clinical trials and studies and patient registries
- Support groups and other special programs for volunteers and their families
LocationsAll across the United States.
ContactFor more information, please contact any of the centers located within NIA's directory of Alzheimer's Research Centers
Alzheimer’s Disease Neuroimaging Initiative-Depression Project
EligibilityIf you match the below criteria, you may qualify for this study:
- In good health
- Age 65+
- Currently experiencing symptoms of depression
- Fluent in English
- Willing to undergo one MRI scan and one PET scan
- Willing to allow the collection of blood for testing
- Have a study partner – a friend or relative who can attend all clinical visits
LocationsThe ADNI-D study will take place at two clinical sites across the United States. For the West Coast operation, volunteers will be recruited at the Langley Porter Psychiatric Institute located at the UCSF Parnassus campus as well as the Memory and Aging Center located at the UCSF Mission Bay campus. For the East Coast, volunteers will be recruited at the University of Pittsburgh.
ContactIf interested in participating with your corresponding ADNI-D site, please call one of the numbers listed below.
Advancing Research and Treatment for Frontotemporal Lobar Degeneration
EligibilityMust meet one of the following research diagnostic criteria for a Frontotemporal lobar degeneration (FTLD) syndrome: behavioral variant frontotemporal dementia (bvFTD), primary progressive aphasia (PPA), semantic variant primary progressive aphasia (svPPA), nonfluent variant primary progressive aphasia (nfvPPA), frontotemporal dementia with amyotrophic lateral sclerosis (FTD/ALS), amyotrophic lateral sclerosis alone, corticobasal syndrome (CBS), progressive supranuclear palsy (PSP) or oligosymptomatic PSP (oPSP). Potential subjects must also be between the ages of 40 and 85, able to walk with assistance at the time of enrollment, and have a reliable study partner who can provide an independent evaluation of functioning. Both the subject and informant must be able to speak English and/or Spanish. Subjects must also have a Mini Mental State Exam (MMSE) score between 15 and 30.
LocationsCA, FL, IL, MA, MD, MO, NC, NY, and Canada
ContactFor more information, please see their website.
Parkinson’s Spectrum Disorders Center
EligibilityFor more information, please contact the study coordinators at 415-353-2057 or visit the study webpage
ContactFor more information, please contact the study coordinators at 415-353-2057 or visit the study webpage https://parkinsonspectrum.ucsf.edu/make-clinic-appointment
US Department of Defense – Alzheimer’s Disease Neuroimaging Initiative
EligibilityNationwide, approximately 1,000 may participate in the screening interview and 500 in the Clinical Telephone Interview. The clinical interview will help us identify approximately 400 Vietnam War Veterans who will be referred for the in-person clinic visits. Approximately 300 Vietnam War Veterans will be eligible to complete the entire study.
ContactIf you are a Vietnam-era combat veteran suffering from TBI or PTSD please call 1-800-773-4883 for more information.
The Longitudinal Evaluation of Familial Frontotemporal Dementia Subjects
EligibilityMust be a member of a family with a known mutation, have a reliable informant who personally speaks with or sees that subject weekly, the subject and informant must be fluent in English, the subject must be willing to undergo yearly evaluations for a period of three years, and also be willing to undergo neuropsychological testing and MRI testing.
LocationsCA, FL, MA, MO NY, PA; Canada
ContactPlease contact the Mayo Clinic in Rochester at 507-284-1324 or the Mayo Clinic in Florida at 904-953-6523 for more information.
Neuroimaging in Frontotemporal Dementia
EligibilityParticipants must be between the ages of 45 and 90 and meet criteria for behavioral variant frontotemporal dementia (bvFTD), semantic dementia (SD), progressive nonfluent aphasia (PNFA) or healthy aging. Participants will need a reliable study partner who has frequent contact with the participant, is available to provide information about the participant, and who can accompany the participant to research visits as needed. All participants must be willing and able to undergo testing procedures, including neuroimaging, and agree to longitudinal follow-up.
LocationsCA, MN, MA
ContactFor more information, please contact the study coordinator: Alyssa Caplan – email@example.com, 415-476-0670.
Alzheimer’s Disease Neuroimaging Initiative
EligibilityADNI is seeking people over the age of 55, who are healthy, as well as those with mild memory problems and those who have been diagnosed with mild dementia due to Alzheimer’s disease.
LocationsThere will be 60 clinical sites throughout the USA and Canada, please visit www.ADNI3.org to find a site near you.
ContactTo participate in ADNI3 you may reach our clinical sites once they are open for enrollment by calling 1-888-2-ADNI-95 (1-888-223-6495). You can also visit their website at http://www.adni3.org.
For Those with Dementia in Your Family
The below studies are specifically enrolling families heavily burdened by dementia and/or Alzheimer’s disease (AD). These studies are searching for biologically related family units willing to help broaden research on AD. More information about eligibility may be found by clicking on the study logo. Please contact the study coordinator listed on the pop-up information window with questions about enrollment and study participation
Dominantly Inherited Alzheimer Network
EligibilityCurrently enrolling study participants who are biological adult children of a parent with a mutated gene known to cause dominantly inherited Alzheimer’s disease (PSEN1, PSEN2, and APP mutations). Such individuals may or may or may not carry the gene themselves and may or may not have disease symptoms. This international multi-center longitudinal study is aiming to recruit 600 individuals: 300 expected to be gene carriers who will develop AD and 300 non-demented controls (siblings).
LocationsWA, NY, IN, CA, MA, RI, PA, FL; United Kingdom; Germany; Australia
ContactFor more information about DIAN, please visit the DIAN website or call the DIAN Global Coordinator at 314-286-2683.
The Genetics of Late Onset Alzheimer’s Disease
EligibilityIf your family has two or more living siblings diagnosed with Alzheimer's disease after the age of 60 years and a third family member who has been diagnosed with memory loss or Alzheimer's disease after the age of 50 OR without symptoms of memory loss and is over the age of 60 years, researchers may be very interested in studying your family.
LocationsWe are eager to involve new families from every location.
ContactFor further information please view our LOAD Study Brochure, or contact the National Centralized Repository for Alzheimer's Disease and Related Dementias at 1-800-526-2839 or by e-mail at firstname.lastname@example.org.
National Centralized Repository Family Study
EligibilityIf your family has two or more living members with Alzheimer's disease or symptoms of serious memory loss, researchers may be very interested in studying your family.
LocationsWe are eager to involve new families from every location.
ContactFor further information please view our NCRAD Study Brochure, or contact the National Centralized Repository for Alzheimer's Disease and Related Dementias at 1-800-526-2839 or by e-mail at email@example.com.
For Healthly Individuals Who Want to Help
Various sites across the United States are in need of healthy volunteers to act as controls for dementia related studies. Volunteers for this research may be spouses or caregivers of those suffering from dementia. More information about eligibility may be found by clicking on the study logo. Please contact the study coordinator listed on the pop-up information window with questions about enrollment and study participation.