Participating in Research
Welcome and thank you for your interest in participating in Alzheimer’s disease research efforts! The National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD) often collaborates very closely with research studies and institutions around the world. Through these collaborations, we have compiled a listing of different studies that are currently enrolling subjects and banking samples with NCRAD. We have separated these studies into three categories: “For Those with Dementia”, “For Those with Dementia in Your Family”, and “For Healthy Individuals Who Want to Help”. Please feel free to explore each study by clicking on the study logo. Once clicked, a window will appear offering important information about each study. Information includes location of research sites and how to contact the study coordinator. If you have any additional questions about this webpage, NCRAD Coordinators would be happy to assist. Please call 1-800-526-2839 or email email@example.com to talk with a NCRAD coordinator.
For Those with Dementia
The below studies are specifically enrolling individuals who are currently suffering from various forms of dementia or Alzheimer’s disease (AD). More information about eligibility may be found by clicking on the study logo. Please contact the study coordinator listed on the pop-up information window with questions about enrollment and study participation
4-Repeat Tauopathy Neuroimaging Initiative-Cycle 2
EligibilityIf you are between 40 and 80 years of age with no known history of neurological disease, or with a diagnosis of Progressive Supranuclear Palsy (PSP) or Corticobasal Degeneration (CBD) you may qualify for this.
LocationsCalifornia, Massachusetts, Toronto, Pennsylvania, Minnesota
ContactFor more information, please contact the study coordinators are 415-476-9578 or visit the 4RTNI-2 webpage.
The 90+ Study
EligibilityIf you 90 years of age or older, live in the Southern California area, and willing to undergo clinical assessments, memory testing, and other procedures every 6 months then you may be eligible for this study. Study participants are also asked to agree to undergo one MRI and one amyloid PET scan; as well as, brain donation upon death.
ContactFor more information please visit The 90+ Study website call a study coordinator at 949-768-3635.
Alzheimer’s Biomarkers Consortium – Down Syndrome
EligibilityTogether they will recruit over 500 adults with Down Syndrome, 25 years of age and over.
LocationsCA, KY, MA, MO, NY, PA, WI, and the UK
ContactFor more information, please contact site personnel by visiting this link.
For scientific questions, please email Melissa Parisi MD, PhD at firstname.lastname@example.org and/or Laurie Ryan PhD at: email@example.com.
Alzheimer’s Disease Research Center
EligibilityPlease contact centers for research and volunteer opportunities. For patients and families affected by Alzheimer's disease, the ADCs offer:
- Help with obtaining diagnosis and medical management (costs may vary—Centers may accept Medicare, Medicaid, and private insurance)
- Information about the disease, services, and resources
- Opportunities for volunteers to participate in clinical trials and studies and patient registries
- Support groups and other special programs for volunteers and their families
LocationsAll across the United States.
ContactFor more information, please contact any of the centers located within NIA's directory of Alzheimer's Research Centers
Alzheimer’s Disease Neuroimaging Initiative-Depression Project
EligibilityIf you match the below criteria, you may qualify for this study:
- In good health
- Age 65+
- Currently experiencing symptoms of depression
- Fluent in English
- Willing to undergo one MRI scan and one PET scan
- Willing to allow the collection of blood for testing
- Have a study partner – a friend or relative who can attend all clinical visits
LocationsThe ADNI-D study will take place at two clinical sites across the United States. For the West Coast operation, volunteers will be recruited at the Langley Porter Psychiatric Institute located at the UCSF Parnassus campus as well as the Memory and Aging Center located at the UCSF Mission Bay campus. For the East Coast, volunteers will be recruited at the University of Pittsburgh.
ContactIf interested in participating with your corresponding ADNI-D site, please call one of the numbers listed below.
- University of California San Francisco: 415-476-7046
- University of Pittsburgh Pennsylvania: 412-586-9061
EligibilityMembers of families in whom at least one member has a known disease-associated mutation in one of the major genes that cause f-FTLD: MAPT, GRN, C9orf72 (or other rare genes); autosomal dominant family history of a FTLD syndrome (without a known gene) verified by medical record review or well-documented family history including family members with a medical history consistent with FTLD or a related disorder.
LocationsUniversity of Alabama Birmingham, University of CA, Los Angeles, University of CA San Diego, University of CA San Francisco, Mayo Clinic Florida, Northwestern University Illinois, John Hopkins University Maryland, Massachusetts General Hospital, Mayo Clinic Rochester Minnesota, Washington University St. Louis Missouri, Cleveland Clinic Lou Ruvo Ctr for Brain Health Nevada, Columbia University New York, University of North Carolina Chapel Hill, Case Western Reserve Med Ctr Ohio, University of Pennsylvania in Philadelphia, Nantz National Alzheimer Center Houston Texas, University of Washington in Seattle, University of British Columbia in Canada, University of Toronto in Canada
ContactVisit allftd.org for more information
Parkinson’s Spectrum Disorders Center
EligibilityFor more information, please contact the study coordinators at 415-353-2057 or visit the study webpage
ContactFor more information, please contact the study coordinators at 415-353-2057 or visit the study webpage https://parkinsonspectrum.ucsf.edu/make-clinic-appointment
US Department of Defense – Alzheimer’s Disease Neuroimaging Initiative
EligibilityNationwide, approximately 1,000 may participate in the screening interview and 500 in the Clinical Telephone Interview. The clinical interview will help us identify approximately 400 Vietnam War Veterans who will be referred for the in-person clinic visits. Approximately 300 Vietnam War Veterans will be eligible to complete the entire study.
ContactIf you are a Vietnam-era combat veteran suffering from TBI or PTSD please call 1-800-773-4883 for more information.
Alzheimer’s Disease Neuroimaging Initiative
EligibilityADNI is seeking people over the age of 55, who are healthy, as well as those with mild memory problems and those who have been diagnosed with mild dementia due to Alzheimer’s disease.
LocationsThere will be 60 clinical sites throughout the USA and Canada, please visit www.ADNI3.org to find a site near you.
ContactTo participate in ADNI3 you may reach our clinical sites once they are open for enrollment by calling 1-888-2-ADNI-95 (1-888-223-6495). You can also visit their website at http://www.adni3.org.
Longitudinal Investigation for Enhancing Down Syndrome Research
EligibilityEnrolling adults with Down Syndrome, 25 years and older.
LocationsAZ, CA, GA, KS, KY, IL, MA, MD, NC, OH
ContactFor more information, please reach out to 781-825-1300 or visit the webpage at: firstname.lastname@example.org
Internet-Based Conversational Engagement Clinical Trial
EligibilityCurrently enrolling volunteers aged 75 and older.
LocationsGA, OH, MI
ContactFor more information, call 1-888-ICONECT
Asian Cohort for Alzheimer’s Disease
EligibilityParticipants will be 60 years or older and of Asian Ancestry
LocationsCA, MA, NY and Canada
ContactFor more information on how to participate in ACAD, please visit: https://acadstudy.org/procedure/ Please send an email to email@example.com if you would like to participate or have any questions about this study.
Longitudinal Early-onset Alzheimer’s Disease Study
EligibilityWill enroll and follow 500 cognitively impaired participants and 100 cognitively normal participants ages 40-64 years at approximately 15 sites in the United States.
LocationsAZ, CA, DC, FL, GA, IL, IN, MA, MD, MO, MN, NY, PA, RI, TX
ContactFor more information, please call 307-963-7428 or email firstname.lastname@example.org
For Those with Dementia in Your Family
The below studies are specifically enrolling families heavily burdened by dementia and/or Alzheimer’s disease (AD). These studies are searching for biologically related family units willing to help broaden research on AD. More information about eligibility may be found by clicking on the study logo. Please contact the study coordinator listed on the pop-up information window with questions about enrollment and study participation
Dominantly Inherited Alzheimer Network
EligibilityCurrently enrolling study participants who are biological adult children of a parent with a mutated gene known to cause dominantly inherited Alzheimer’s disease (PSEN1, PSEN2, and APP mutations). Such individuals may or may or may not carry the gene themselves and may or may not have disease symptoms. This international multi-center longitudinal study is aiming to recruit 600 individuals: 300 expected to be gene carriers who will develop AD and 300 non-demented controls (siblings).
LocationsWA, NY, IN, CA, MA, RI, PA, FL; United Kingdom; Germany; Australia
ContactFor more information about DIAN, please visit the DIAN website or call the DIAN Global Coordinator at 314-286-2683.
The Genetics of Late Onset Alzheimer’s Disease
EligibilityIf your family has two or more living siblings diagnosed with Alzheimer's disease after the age of 60 years and a third family member who has been diagnosed with memory loss or Alzheimer's disease after the age of 50 OR without symptoms of memory loss and is over the age of 60 years, researchers may be very interested in studying your family.
LocationsWe are eager to involve new families from every location.
ContactFor further information please view our LOAD Study Brochure, or contact the National Centralized Repository for Alzheimer's Disease and Related Dementias at 1-800-526-2839 or by e-mail at email@example.com.
National Centralized Repository Family Study
EligibilityIf your family has two or more living members with Alzheimer's disease or symptoms of serious memory loss, researchers may be very interested in studying your family.
LocationsWe are eager to involve new families from every location.
ContactFor further information please view our NCRAD Study Brochure, or contact the National Centralized Repository for Alzheimer's Disease and Related Dementias at 1-800-526-2839 or by e-mail at firstname.lastname@example.org.
For Healthly Individuals Who Want to Help
Various sites across the United States are in need of healthy volunteers to act as controls for dementia related studies. Volunteers for this research may be spouses or caregivers of those suffering from dementia. More information about eligibility may be found by clicking on the study logo. Please contact the study coordinator listed on the pop-up information window with questions about enrollment and study participation.